(Left) Three-dimensional microCT-based virtual histology allows full assessment of an E12.5 mouse embryo (cut-away). John T. Johnson, Mark S. Hansen, Isabel Wu, Lindsey J. Healy, Christopher R. Johnson, Greg M. Jones, Mario R. Capecchi, Charles Keller. (2006) Virtual histology of transgenic mouse embryos for high-throughput phenotyping. PLoS Genet 2(4):e61[COVER ARTICLE] [PubMed UID 16683035]. ,

(Right) “Virtual” Sectioning E12.5 (David Roland Rodriguez, CCRI, UTHSCSA).

© Copyright 2007 Numira Biosciences Inc. All Rights Reserved
Numira's Focus

Numira™ Biosciences is a specialty imaging company focused on building a catalog of novel tools and solutions that address a number of important, but challenging needs in research and drug development in the areas of:

  Genomics Drug Discovery
  Developmental Biology Drug Efficacy
  Mechanisms of Disease Toxicity

The Company was formed to develop and commercialize several imaging and reporter technologies invented by Charles Keller, M.D., a Board Certified Pediatric Hematologist Oncologist, and pediatric cancer researcher.   As a result of his work in developing therapies for rhabdomyosarcoma, a rare form of pediatric cancer, he and his colleagues developed R&D tools that leverage recent, powerful advances in imaging, genetics, and reporter technologies.  Dr. Keller and the other founders of Numira believe that providing access to these novel tools is essential for the scientific and drug development communities.

In mid-2006, Numira began delivering on the vision of its founders with the market launch of its first product, Virtual Histology™.  This product allows researchers to more efficiently, and quantitatively, screen potential drug and chemical product candidates for morphological defects in developing embryos and fetuses.  This technology represents a revolutionary leap forward in teratology as well as a number of other soft tissue and skeletal applications.

In early-2007, Numira acquired a leading visualization software company, Visual Influence Inc, to further enhance its software applications through innovative image processing and analysis, graphics-based acceleration, and volume visualization. Now customers can view their data in 3D, focus on specific anatomical structures and generate quantitative assessments for their region of interest. 

The future looks very bright.  Our development pipeline is robust and will ensure a steady stream of new product and service introductions over the next 2 – 3 years.