Professional Analysis, Diagnostic Consultation and Expert Investigational Analysis

Transgenic Phenotyping
Pre-Tox Screening
Numira’s Expertise
Numira’s Diagnostic and Reporting Services

Armed with Virtual Histology™, Numira’s team of biomedical imaging software engineers, Board Certified Pediatric Radiologists, Developmental Biologists, we are dedicated to providing unparalleled imaging services, diagnostic consultation and expert investigational analysis.

Transgenic Phenotyping

Transgenic and knockout animal models provide valuable insights and understanding into gene function and the pathways for therapeutic development. These animal models often pose challenges in terms of unexpected phenotypes which may require extensive analysis and investigational research. Additionally, the ability to identify potentially subtle off target effects of certain compounds on transgenic mice as compared to the wild-type control, elucidates critical information about the role of the compound in relation to the target gene. Numira’s small animal imaging services, diagnostic consultation and expert investigational analysis offer detailed phenotypic analysis and valuable guidance in these situations.

Pre-Tox Screening

Many pharmaceutical and chemical companies are increasingly performing early stage teratology screening of viable compounds to determine their toxicity before dedicating resources to further development. Numira’s small animal imaging services, diagnostic consultation and expert investigational analysis offer these companies a turn-key, early stage screening mechanism to identify potential teratogenic effects empowering informed drug development decisions.

Numira’s Expertise

  • Developmental Biologists
  • Embryologists
  • Teratologists
  • Board Certified Radiologists

Numira’s Diagnostic and Reporting Services

  • Quantitative Analysis
    • Expert quantitative analysis performed by trained laboratory technician, small animal imaging specialist or radiologist to provide detailed measurements such as volume, shape, dimension, and distance of specific ROI’s.
  • Diagnostic Interpretation
    • Radiologist to perform interpretation of Virtual HistologyTM data sets to provide diagnostic overview with clear, concise report format offering researchers a comprehensive review of the defects and malformations within the specimen.
  • Investigational Analysis
    • In concert with the reading Radiologist, a Developmental Biologist to research applicable phenotypes, defects and malformations of significance associated with gene function and expression or potential teratogenic effects associated with a given compound. Report to include detailed description as supported by literature.