 
RI and PET co-registration in the central nervous system and upper torso of a normal adult mouse, side view. Co-registration was achieved using a Multi-Modality Chamber for reproducible positioning in separate MRI and microPET scans Ali N. Bahadur, Isabel Q. Wu, David M. Weinstein, M. Duff Davis, David A. Lewis, Peter Kochunov, Charles Keller. “Stealth, Safe Multimodality Chamber for Co-registered Anatomical and Molecular Small Animal Imaging,” Lab Animal.
When placed inside a mouse cadaver, a tritium luminescence source has a transmission of 93% through the chamber. Numira's Multi-Modality Imaging Chamber featured in the September 2007 issue of Lab Animal. Challenge: Image Co-Registration
Registration of multi-modal imaging data is a complex problem that has challenged the medical imaging community over the past fifteen years. Numira's Multi-Modality Imaging Chamber presents a novel solution for small animal imaging facilities seeking increased control and the ability to easily conduct multi-modality studies. The Multi-Modality Imaging Chamber Design of the Multi-Modality Imaging Chamber The Multi-Modality Imaging Chamber for Small Animal Imaging facilitates the co-registration of anatomical and functional images by enabling the use of several imaging modalities during the same study. The Chamber design also dramatically lowers infection risk for test subjects and animal colonies. The customized polyurethane foam bed allows reproducible rigid staging of the animal accommodating both 2D-3D/3D-3D co-registration via fiducial markers. By avoiding restraints that obscure the field of view, the foam bed is essentially “invisible” because its density is similar to air. Design of the Multi-Modality Imaging Chamber
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