Virtual Histology™

Virtual Histology™ is a new imaging technology that combines proprietary contrast agents, protocols, and software, with microCT imaging. Virtual Histology is establishing the new “gold” standard in soft tissue and skeletal imaging for the following reasons:

• The results are crystal clear. The crisp, clean images provide a degree of anatomic detail that mimics routine histology as viewed by light microscopy.
• The smallest details are made visible in the smallest specimens. Virtual Histology™ can provide greater than 6µm isometric voxel resolution enabling detailed analysis.
• Virtual Histology is non-destructive. The digital, 3D nature of our technology allows the researcher to easily change the viewing angle from axial, sagittal, coronal and even arbitrary oblique planes based on the anatomic feature of interest offering new perspectives – all without sectioning the specimen.  Because our processing doesn’t compromise the sample, upon request we will return the tissue for further investigation.
• Virtual Histology enables detailed 3D analysis of individual organs and other regions of interest. Our segmentation tools enable quantitative analysis in 3D.  Linear, volume, surface, and shape statistics are routine.  An example application would be the detection and assessment of subtle changes in developmental growth patterns, allowing an increased understanding of the morphological effects of drug and transgenic models – an invaluable tool for pre-clinical efficacy assessment and toxicology.
• You will know – for sure. Questionable or insufficient imaging results from other imaging approaches or standard evaluation techniques lead to further investigation and additional research projects and investment.  With our services, you will capture more data than traditional methods.  If there’s an unexpected finding, wouldn’t you rather know sooner than later? 

The bottom line is that you will know the answers to your toughest research projects – sooner and more definitively than ever before.  You’ll have less wasted effort; more cost-savings; and will be able to get the drugs and disease treatments to market sooner.

Our custom imaging services are coupled with the exact expertise that your study requires. Whether it is early stage compound screening, pilot toxicology studies, or transgenic phenotyping, we will tailor a protocol to best suit your study’s objectives.

High-Performance Visual Analytics

High-Performance Visual Analytics are critical for today’s complex small animal imaging study needs.  Numira has expertise across a broad range of domains:

• medical imaging
• scientific data management
• image processing and analysis
• graphical rendering
• 3D volume visualization
• high-performance computing
• cross-platform software development
• GPU programming